refractive errors changes during uveitis activation phase

نویسندگان

مهسا ضامنی

m zameni ophthalmic research center, shahid beheshti university of medical sciences, tehran, iranتهران- پاسداران- بوستان نهم- خیابان پایدارفرد (خیابان امیر ابراهیمی)- پلاک 23- مرکز تحقیقات چشم مهدی یاسری

m yaseri دانشکده بهداشت و آمار- دانشگاه علوم پزشکی تهران مسعود سهیلیان

m soheilian ophthalmic research center, shahid beheshti university of medical sciences, tehran, iranتهران- پاسداران- بوستان نهم- خیابان پایدارفرد (خیابان امیر ابراهیمی)- پلاک 23- مرکز تحقیقات چشم

چکیده

purpose: to evaluate the role of active uveitis on refractive errors changes. methods: a cohort single group study was conducted on patients with acute or recurrent uveitis. cyclorefraction was performed in both phases of active and quiescent. sphere, cylinder and sphere equivalent power were compared in active and quiescent phases and analyzed statistically. results: sixty-six patients (eighty-eight eyes) were enrolled in this study. mean age was 34 ± 14 years (range 6 to 65). 61.7% of the patients were women (54 out of 88). among the 46 cases of anterior uveitis 25 eyes (54%) were in acute and 21 eyes (46%) were in recurrent phase. spherical power changes were statistically significant in anterior non-granolumatous uveitis (p=0.039) and intermediate uveitis (p=0.002). spherical equivalent power changes were statistically significant different in intermediate uveitis (p=0.005) and panuveitis (p=0.096) groups. cylinder power did not show any significant changes in none of the above mentioned groups. this study showed that, in anterior non-granolumatous uveitis and panuveitis, spherical and spherical equivalent power changes were shifted toward myopia during active uveitis and just spherical power changes were shifted toward hyperopia in intermediate uveitis. regression analysis disclosed that only activity of uveitis and age had a statistically significant effect on the spherical power changes after adjustment (p<0.001 and p=0.036, respectively). evaluating spherical equivalent power changes, regression analysis showed that activity of uveitis and anatomic location of uveitis had a statistically significant effect (p=0.003 and p=0.001, respectively). conclusion: active uveitis plays an effective role on changing the refractive powers. the shift of these changes depends on the inflammated anatomical area; in anterior uveitis it is toward myopia and in intermediate uveitis it is toward hyperopia.

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